Joint disease, mainly osteoarthritis, is a potentially debilitating condition that affects the soft tissue matrix that “cushions” our joints. To help support the structural integrity of joint cartilage, Glucosamine, Chondroitin, and MSM all offer significant benefits.† Glucosamine and chondroitin sulfate are both integral components of healthy joint tissue and are the forms that have been used in the major clinical trials. OptiMSM® provides a synergistic benefit, as it is a source of sulfur, a trace mineral that is an important structural component of joint cartilage. We use the highest quality raw materials that are identical to those used in the major clinical trials.